Which of the following are incorrectly paried ?

Options

A. B cells `:` Insulin
B. F cells `:` Gastrin
C. A cells `:` Glucagon
D. D cells `:` Somatostatin

Answer

To determine which of the pairs is incorrectly matched, we will analyze each pair of cells and their corresponding hormones or substances secreted by the pancreas.

1. **Identify the pairs:**
- A-cells → Glucagon
- B-cells → Insulin
- D-cells → Somatostatin
- F-cells → Gastrin

2. **Check the functions of the cells:**
- **A-cells (Alpha cells)**: These cells are known to secrete glucagon, which functions to increase blood glucose levels. This match is correct.
- **B-cells (Beta cells)**: These cells secrete insulin, which helps to lower blood glucose levels. This match is also correct.
- **D-cells (Delta cells)**: These cells secrete somatostatin, which regulates the endocrine system and inhibits the secretion of other hormones. This match is correct as well.
- **F-cells**: These cells are responsible for secreting pancreatic polypeptide, not gastrin. Gastrin is secreted by G-cells in the stomach, not by F-cells. Therefore, this match is incorrect.

3. **Conclusion**:
The incorrectly paired option is F-cells → Gastrin. The correct pairing should be F-cells → Pancreatic polypeptide.

### Summary of the solution:
- A-cells → Glucagon (Correct)
- B-cells → Insulin (Correct)
- D-cells → Somatostatin (Correct)
- F-cells → Gastrin (Incorrect, should be Pancreatic polypeptide)