The classical definition of hormone is a follows: 

Options

A. Hormone as chemical produced by endocrine glands and released into blood and transported to a distantly located target organ.
B. Hormones are non-nutrient chemicals which acts as intercelluclar messengers and a produced in trace amounts
C. Hormones are non-nutrient chemicals which act as intracellular messengers and are produced in trace amounts
D. Both 2 and 3

Answer

1