Match the column I and II, and choose the correct combination from the option given
`{:(,"Column I ",,"Column II"),(a., "Membrane bound receptor",1.,LH),(b., "Intracellular receptor",2., FSH),(,,3.,"Estrogen"),(,,4.,"Thyroxine"),(,,5.,"Insuline"),(,,6.,"Testosterone"):}`

Options

A. a-3,4 and 5, b-1,2 and 6
B. a-1,2 and 5, b-3,4 and 6
C. a-3,4 and 6, b -1,2 and 5
D. a-1,2 and 6, b - 3 ,4 and 5

Answer

To solve the matching question, we need to identify which hormones belong to the categories of membrane-bound receptors and intracellular receptors. Here’s a step-by-step breakdown of the solution:

### Step 1: Identify the Types of Hormones
- **Membrane-bound receptors**: These receptors are typically associated with peptide hormones. They do not enter the cell but bind to receptors on the cell membrane.
- **Intracellular receptors**: These receptors are associated with steroid hormones and some amino acid derivatives. These hormones can cross the cell membrane and bind to receptors inside the cell.

### Step 2: Classify the Hormones
Now, let's classify the hormones provided in Column II based on their receptor types:

1. **LH (Luteinizing Hormone)**: This is a peptide hormone and binds to membrane-bound receptors.
2. **FSH (Follicle-Stimulating Hormone)**: This is also a peptide hormone and binds to membrane-bound receptors.
3. **Estrogen**: This is a steroid hormone and binds to intracellular receptors.
4. **Thyroxine**: This is an amino acid derivative and binds to intracellular receptors.
5. **Insulin**: This is a peptide hormone and binds to membrane-bound receptors.
6. **Testosterone**: This is a steroid hormone and binds to intracellular receptors.

### Step 3: Match the Hormones with the Receptor Types
Now we can match the hormones from Column I with their corresponding receptor types in Column II:

- **Membrane-bound receptors**:
- a. Membrane bound receptor → 1. LH
- a. Membrane bound receptor → 2. FSH
- a. Membrane bound receptor → 5. Insulin

- **Intracellular receptors**:
- b. Intracellular receptor → 3. Estrogen
- b. Intracellular receptor → 4. Thyroxine
- b. Intracellular receptor → 6. Testosterone

### Step 4: Write the Final Matches
Now we can summarize the matches:
- a. Membrane bound receptor → 1. LH
- a. Membrane bound receptor → 2. FSH
- a. Membrane bound receptor → 5. Insulin
- b. Intracellular receptor → 3. Estrogen
- b. Intracellular receptor → 4. Thyroxine
- b. Intracellular receptor → 6. Testosterone

### Final Answer
The correct combinations are:
- a → 1, 2, 5 (LH, FSH, Insulin)
- b → 3, 4, 6 (Estrogen, Thyroxine, Testosterone)