During growth and differentiation of oogenesis the nucleus of primary oocytes remains in

Options

A. Telophase stage
B. S-phase
C. Prolonged meiotic pachytene stage
D. Prolonged meiotic diplotene stage

Answer

**Step-by-Step Solution:**

1. **Understanding Oogenesis**: Oogenesis is the process of egg (ovum) formation in females. It involves several stages of growth and differentiation of oocytes.

2. **Primary Oocyte Formation**: Before birth, the primary oocyte is formed from the oogonia through mitosis. The primary oocyte is diploid (2N).

3. **Arrested Development**: The primary oocyte does not complete its meiosis immediately. Instead, it enters a stage where it is arrested. This arrest occurs in a specific phase of meiosis.

4. **Identifying the Arrest Phase**: The primary oocyte remains arrested in the diplotene stage of prophase I of meiosis. This is known as the diplotene phase, which is part of the first meiotic division.

5. **Resumption of Meiosis**: The primary oocyte will remain in this arrested state until puberty. Upon reaching puberty, the primary oocyte resumes meiosis, completing the first meiotic division to form a secondary oocyte and a polar body.

6. **Conclusion**: Therefore, during the growth and differentiation of oogenesis, the nucleus of the primary oocyte remains in the prolonged meiotic diplotene phase.

**Final Answer**: The nucleus of primary oocytes remains in the prolonged meiotic diplotene phase.

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