Mark the correct match .

Options

A. Turner's syndrome - 45 + XO
B. Phenylketonuria - 44 + XYY
C. Klinefelter's syndrome - 44 + XXY
D. Thalassemia - 44 + YO

Answer

To solve the question of matching the correct genetic conditions with their respective chromosomal complements, we will analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understanding Normal Chromosomal Count**:
- In humans, a normal somatic cell has a diploid number of chromosomes, which is 46 (2N = 46).
- This consists of 44 autosomes and 2 sex chromosomes (XX for females and XY for males).

2. **Analyzing Klinefelter Syndrome**:
- Klinefelter syndrome occurs in males who have an extra X chromosome, resulting in a chromosomal complement of 44 + XXY.
- This means the total number of chromosomes is 47 (44 autosomes + 3 sex chromosomes).

3. **Identifying Other Conditions**:
- **Phenylketonuria (PKU)**: This is a Mendelian disorder caused by a defect in a single gene, not related to chromosomal number. It is not associated with a specific chromosomal complement.
- **Thalassemia**: Similar to PKU, thalassemia is also a Mendelian disorder caused by mutations in genes related to hemoglobin production, again not linked to chromosomal count.
- **Turner Syndrome**: This condition occurs in females where one X chromosome is missing, leading to a chromosomal complement of 44 + XO (totaling 45 chromosomes).

4. **Evaluating the Options**:
- Klinefelter syndrome is correctly matched with 44 + XXY.
- Turner syndrome should be matched with 44 + XO, but if it is presented as 45 + XO, it is incorrect.
- Both PKU and thalassemia are not chromosomal disorders, so they do not have a chromosomal complement.

5. **Conclusion**:
- The correct match is Klinefelter syndrome with the genetic complement of 44 + XXY. This is the only option that accurately reflects a chromosomal disorder.

### Final Answer:
The correct match is **Klinefelter syndrome - 44 + XXY**.

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