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Most common prevalent Mendelian disorder...

Most common prevalent Mendelian disorders are

A

Haemophilia, eystic fibrosis and Down's syndrome

B

Sickle cell anaemia, colour blindness and Turner's syndrome

C

Colour blindness, phenylketonuria and Thalalassemia

D

Phenylketonuria , Thalalassemia and Klinefeltans syndrome

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### Step-by-Step Solution: 1. **Understanding Mendelian Disorders**: - Mendelian disorders are genetic disorders caused by a defect in a single gene. They can be inherited in a predictable manner based on Mendel's laws of inheritance. 2. **Differentiating Between Mendelian and Chromosomal Disorders**: - Mendelian disorders involve mutations or defects in individual genes, while chromosomal disorders involve abnormalities in the number or structure of chromosomes (e.g., Down syndrome, Turner syndrome). 3. **Identifying Common Mendelian Disorders**: - Common Mendelian disorders include: - **Hemophilia**: A sex-linked recessive disorder affecting blood clotting. - **Cystic Fibrosis**: An autosomal recessive disorder affecting the respiratory and digestive systems. - **Sickle Cell Anemia**: An autosomal recessive disorder affecting hemoglobin in red blood cells. - **Color Blindness**: A sex-linked recessive disorder affecting color perception. - **Phenylketonuria (PKU)**: An autosomal recessive disorder affecting metabolism. - **Thalassemia**: An autosomal recessive disorder affecting hemoglobin synthesis. 4. **Analyzing the Options Provided**: - The question likely provides multiple options, some of which may include both Mendelian and chromosomal disorders. - For example, if the options include hemophilia, cystic fibrosis, Down syndrome, and Turner syndrome, we can identify which are Mendelian. 5. **Eliminating Chromosomal Disorders**: - From the options, identify and eliminate any that are chromosomal disorders (e.g., Down syndrome, Turner syndrome, Klinefelter syndrome). 6. **Final Selection of Common Mendelian Disorders**: - After eliminating the chromosomal disorders, the remaining options will be the common Mendelian disorders. 7. **Conclusion**: - The most common prevalent Mendelian disorders are hemophilia, cystic fibrosis, sickle cell anemia, color blindness, phenylketonuria, and thalassemia.
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