Name the histone proteins which together forms the histone octamer structure

Options

A. `H_(1), H_(2)A, H_(2)B" and "H_(3)`
B. `H_(1), H_(2)A, H_(2)B" and "H_(4)`
C. `H_(2)A, H_(2)B, H_(3)" and "H_(4)`
D. `H_(2)A, H_(2)B, H_(3), H_(4)" and "H_(1)`

Answer

To answer the question regarding the histone proteins that form the histone octamer structure, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Histone Octamer**:
- The histone octamer is a protein complex that plays a crucial role in the packaging of DNA into a compact structure known as chromatin.

2. **Composition of the Histone Octamer**:
- The histone octamer consists of 8 histone proteins. Specifically, it is made up of 2 copies of 4 different core histone proteins.

3. **Identifying the Core Histone Proteins**:
- The four core histone proteins that make up the octamer are:
- H2A
- H2B
- H3
- H4

4. **Clarifying the Role of H1**:
- It is important to note that while H1 is a histone protein, it is not part of the histone octamer. H1 is involved in the higher-order structure of chromatin but does not contribute to the octamer itself.

5. **Final Answer**:
- Therefore, the histone proteins that together form the histone octamer structure are H2A, H2B, H3, and H4.