Which is not true regarding VNTRs and SSR?

Options

A. They are tandem repeats
B. They are excellent genetic markers
C. They vary greatly from individual to individual
D. They constitute 10% of human genome

Answer

To determine which statement is not true regarding Variable Number Tandem Repeats (VNTRs) and Short Tandem Repeats (STRs), we will analyze the characteristics of both VNTRs and STRs based on the information provided.

### Step-by-Step Solution:

1. **Definition of VNTRs and STRs**:
- VNTRs (Variable Number Tandem Repeats) are sequences in DNA where a short nucleotide sequence is repeated a variable number of times.
- STRs (Short Tandem Repeats) are similar but consist of shorter repeat units.

**Hint**: Remember that VNTRs have longer repeat units compared to STRs.

2. **Nature of Tandem Repeats**:
- Both VNTRs and STRs are classified as tandem repeats, meaning they consist of repeated sequences arranged in a head-to-tail fashion.

**Hint**: Think about how these sequences are structured in the DNA.

3. **Use in DNA Fingerprinting**:
- VNTRs and STRs are widely used in DNA fingerprinting because they are highly polymorphic, meaning they vary greatly among individuals.

**Hint**: Consider why variability is important in identifying individuals.

4. **Genetic Markers**:
- VNTRs and STRs are considered excellent genetic markers due to their variability and abundance in the genome.

**Hint**: Recall the importance of genetic markers in forensic science and paternity testing.

5. **Proportion in the Human Genome**:
- The statement that VNTRs and STRs constitute 10% of the human genome is incorrect. In fact, they make up about 50% of the human genome.

**Hint**: Think about how much of the genome is made up of repetitive sequences.

### Conclusion:
The statement that "VNTRs and STRs constitute 10% of the human genome" is not true. The correct information is that they constitute approximately 50% of the human genome.

### Final Answer:
The incorrect statement regarding VNTRs and STRs is that they constitute 10% of the human genome.

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