HOFMANN RULE

Dehydrohalogenation OF HOFmann Elimination || Heme (HOFmann Exhaustive Methylation Elimination) ||Dehalogenation

Hofmann Exhaustive Methylation

In which product formation takes place according to Hofmann's rule

In E_2 elimination, some compounds follow Hofmann's rule which means:

In which product formation takes place according to Hofmann's rule ?

Why is it difficult topreparepure amines by Hofmann’s ammonolysis?