Two hormones ….. (a) ….. and ……. (b) …… synthesize in hypothalamus and transport in pituitary gland through …… (c ) …….. and ……. (d) ……. respectively.

Options

A. a = oxytocin `rArr` c = portal circulation
b = ADH `rArr ` d = direct release
B. a = ADH `rArr` c = axonal transport
b= TSHRF `rArr` d = portal circulation
C. a = ACTH `rArr ` c = axonal transport
b = MSH `rArr ` d= portal circulation
D. a = TSHRF `rArr ` c = axonal transport
b = ADH `rArr` d = portasl circulation

Answer

To answer the question, we need to identify the hormones synthesized in the hypothalamus, how they are transported to the pituitary gland, and the specific pathways involved.

### Step-by-Step Solution:

1. **Identify the Hormones**:
- The two hormones synthesized in the hypothalamus are **Oxytocin** and **Antidiuretic Hormone (ADH)**, also known as **Vasopressin**.

2. **Transport Mechanism**:
- Oxytocin and ADH are transported to the **posterior pituitary gland** through **neural connections**. This is because the posterior pituitary is an extension of the hypothalamus and utilizes axonal transport.

3. **Anterior Pituitary Hormone**:
- The hypothalamus also produces releasing factors that act on the anterior pituitary. One such releasing factor is **Thyroid Stimulating Hormone Releasing Factor (TSHRF)**.

4. **Transport to Anterior Pituitary**:
- TSHRF is transported to the **anterior pituitary gland** through **portal circulation**. This is a network of blood vessels that connects the hypothalamus to the anterior pituitary.

5. **Final Answer**:
- (a) Oxytocin, (b) ADH, (c) neural connections, (d) portal circulation.

### Complete Answer:
Two hormones (a) **Oxytocin** and (b) **Antidiuretic Hormone (ADH)** are synthesized in the hypothalamus and transported to the pituitary gland through (c) **neural connections** and (d) **portal circulation** respectively.