Which statement is not correct regarding to stickle cell anaemia :-

Options

A. This is autosomal linked recessive trait
B. Heterzygous `(Hb^(A)Hb^(S))` are resistant to malarial disease
C. Heterozygous `(Hb^(A)Hb^(S))` individuals are diseased phenotype
D. Defect is caused by the substitution of glutamic acid (Glu) by valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule

Answer

C