Assertion :- For sequencing, the total DNA from a cell is isolated and converted into random fragments.
Reason : DNA is a long polymer & there are technical limitations in sequencing very ling pices of DNA.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are trur but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is Flase.
D. If both Assertion & Reason are false.

Answer

To solve the question, we will analyze the assertion and the reason provided.

### Step-by-Step Solution:

1. **Understanding the Assertion**:
- The assertion states that for sequencing, the total DNA from a cell is isolated and converted into random fragments.
- This is a common practice in DNA sequencing techniques, such as shotgun sequencing, where the entire genome is broken down into smaller, manageable pieces for analysis.

2. **Understanding the Reason**:
- The reason given is that DNA is a long polymer, and there are technical limitations in sequencing very long pieces of DNA.
- This is true because DNA molecules can be extremely long, making it impractical to sequence them in one continuous piece. Instead, breaking them into smaller fragments allows for more efficient sequencing.

3. **Evaluating the Relationship**:
- The assertion is correct because it accurately describes a step in the DNA sequencing process.
- The reason is also correct as it explains why the assertion is necessary; the long nature of DNA presents challenges in sequencing.

4. **Conclusion**:
- Both the assertion and the reason are correct, and the reason provides a valid explanation for the assertion.

### Final Answer:
- Both the assertion and the reason are correct, and the reason explains the assertion. Therefore, the answer is option number one.