Why are thalassemia and hemophilia categorized as Mendelian disorders ? Write the symptoms of these diseases .Explain their pattern of inheritance in humans.
( b) Write the genotypes of the normal parents producing a heamophilic son.

Explanation

Thalassemia and heamophilea are categorzed as Mendelian disorders because they occur by mutation in a single gene. Their mode of inderitance follows the principles of Mendelian genetics .Mendelian disorders can be autosomal domiant (muscular dystrophy) .
Symptoms of Thalassemia - This is an autosomal - recessive blood disorder .The disorder is due to reduced synthesis of globin chains leading to leading to anamia. In a Thalassemia production of a globin chain is affected while in â globin chain is affeted .Genes for thalasseimia of one or more of the four genes while â thalassemia á are HbA1 and HbA2 on chromosomes 16 and is caused due to mutation or deletion of one or more of the four genes while â Thalassemia is controlled by a single gene HBB located on chromosme 11 of each parent .

Symptoms of Haemophilia-Person suffering from this disease does not develop proper blood clothing mechansims .A hemophilic patient suffers from non- stop bleeding even on a simple cut which may lead to death.
Pattern of Inheritance of Haemophilia : Haemophilia is an x-linked genetic disoder compared to female males have higher chances of getting afferted .
1.A carrier female `(x^h Y)`s married to a normal male .

When a normal male marries a carrier female . they can produce a hamophilic son , so the genetype of the parents would be XY and `X^(h)X`