Commonly used vectors for human genome sequencing are

Options

A. T/A Cloning Vectors
B. T-DNA
C. BAC and YAC
D. Expression Vectors

Answer

C

Explanation

`**" "`For sequencing, the total DNA from a cell is isolated and converted into random fragments of relatively smaller sizes (recall DNA is a very long polymer, and there are technical limitations in sequencing very long pieces of DNA) and cloned in suitable host using specialised vectors.
`**" "`The cloning resulted into amplification of each piece of DNA fragment so that it subsequently could be sequenced with ease.
`**" "`The commonly used hosts were bacteria and yeast, and the vectors were called as BAC (bacterial artificial chromosomes), and YAC (yeast artificial chromosomes).