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Transition mutation is due to replacemen...

Transition mutation is due to replacement of

A

GC by TA

B

AT by CG

C

CG by GC

D

AT by GC

Text Solution

Verified by Experts

The correct Answer is:
D
Substitution (Replacement) : In substitution a nitrogen base is changed with another base. It is of two types - transition and tranversion.
1. Transition : Purine is replaced by purine `(A hArr G)` while pyrimidine is replaced by pyrimidine `(C hArr T, C hArr U)`.
2. Transversion : Purine is replaced by pyrimidine `(A rarr C)` while pyrimidine is replaced by purine `(C rarr A)`. e.g.: `SCA (GAG rarr GUG)`.
A classical example of point mutation is a change of single base pair in the gene for beta globin chain that results in the change of amino acid residue glutamate to valine. It results into a diseased condition called as sickle cell anemia.
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