Can we define the temperature of(A)vacuum,(B)a single molecule?

Can we define the temperature of a single molecule?

Statement-I : Temperature is a macroscopic concept Statement-2 : It is the average behavior of large number of molecules which constitute a system. Temperature of a single molecule cannot be defined.

Can we increase the temperature of a gas without supplying heat to it?

Can we measure the temperature of the object by touching it ?

Can we change the ratio of atoms in the molecules of the substances while balancing the equation ?

Can temperature be assigned to a vacuum?