Binding of oxygen with haemoglobin is primarily related to `:`

Options

A. Partial pressure of `O_(2)`
B. Partial pressure of `CO_(2)`
C. `H^(+)` ion concentration
D. Temperature

Answer

To solve the question regarding the binding of oxygen with hemoglobin, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Hemoglobin Function**: Hemoglobin is a protein in red blood cells responsible for transporting oxygen from the lungs to the tissues and returning carbon dioxide from the tissues back to the lungs.

**Hint**: Remember that hemoglobin's primary role is to carry gases like oxygen and carbon dioxide.

2. **Identify Factors Affecting Binding**: The binding of oxygen to hemoglobin is influenced by several factors, including the concentration of oxygen, carbon dioxide, hydrogen ions, and temperature.

**Hint**: Consider what physical or chemical properties might affect gas binding to proteins.

3. **Focus on Partial Pressure**: The binding of oxygen to hemoglobin is primarily related to the partial pressure of oxygen (pO2). The higher the pO2, the more oxygen will bind to hemoglobin. This is due to the principle of gas exchange where gases move from areas of higher concentration to lower concentration.

**Hint**: Think about how gases behave in different concentrations and how that affects their binding to proteins.

4. **Evaluate Other Options**:
- **Partial Pressure of Carbon Dioxide**: While it can influence oxygen binding indirectly (through the Bohr effect), it is not the primary factor.
- **H+ Ion Concentration**: This also affects the binding indirectly but is not the primary factor.
- **Temperature**: Changes in temperature can affect hemoglobin's affinity for oxygen, but again, it is not the primary factor.

**Hint**: Analyze each option critically to determine which one directly relates to the binding of oxygen.

5. **Conclusion**: Based on the understanding that the binding of oxygen to hemoglobin is primarily influenced by the partial pressure of oxygen, the correct answer is:

**Answer**: Partial pressure of Oxygen.