Which of the following statement `//` s is `//` are correct ?
A- A high concentration of carbonic anhydrase is present in RBC.
B- Minute quantities of carbonic anhydrase is present in plasema.
C-Every 100 ml blood delivers approximately 4 ml of `CO_(2)` to the alveoli.
D- `20-25%` `CO_(2)` is carried by haemoglobin as carbaminohaemoglobin.

Options

A. A,C and D
B. A and D
C. A,B,C and D
D. Only A

Answer

To determine which statements are correct regarding carbonic anhydrase and its role in the transport of carbon dioxide in the blood, let's analyze each statement step by step.

### Step-by-Step Solution:

1. **Statement A: A high concentration of carbonic anhydrase is present in RBC.**
- Carbonic anhydrase is indeed an enzyme that catalyzes the conversion of carbon dioxide and water into carbonic acid, which then dissociates into bicarbonate ions and hydrogen ions. This enzyme is predominantly found in red blood cells (RBCs), where its concentration is significantly higher than in other parts of the blood.
- **Conclusion:** This statement is **correct**.

2. **Statement B: Minute quantities of carbonic anhydrase is present in plasma.**
- While the majority of carbonic anhydrase is found in RBCs, there are indeed small amounts present in the plasma. However, the concentration in plasma is much lower compared to that in RBCs.
- **Conclusion:** This statement is **correct**.

3. **Statement C: Every 100 ml blood delivers approximately 4 ml of CO2 to the alveoli.**
- It is well-established that for every 100 ml of blood, approximately 4 ml of carbon dioxide is delivered to the alveoli for exhalation. This is part of the respiratory gas exchange process.
- **Conclusion:** This statement is **correct**.

4. **Statement D: 20-25% CO2 is carried by hemoglobin as carbaminohemoglobin.**
- Carbon dioxide is transported in the blood in three forms: dissolved in plasma (7%), as bicarbonate ions (70%), and bound to hemoglobin as carbaminohemoglobin (approximately 20-25%). This statement accurately reflects the transport mechanism of CO2.
- **Conclusion:** This statement is **correct**.

### Final Conclusion:
All four statements (A, B, C, and D) are correct.