State Munch mass flow hypothesis. Demonstrate the principle with neat diagram.

Explanation

Fisher and Race hypothesis: Rh factor involves three different pairs of alleles located on three different closely linked loci on the chromosome pair. This system is more Dord Dord commonly in use today, and uses the .Cde. nomenclature. In the given figure, three pairs of Rh alleles (Cc, Dd and Ee) occur at 3 different loci on homologous chromosome Eore pair-1. The possible genotypes will be one C ord, one E ore from each chromosome. For e.g. CDE/cde, CdE/cDe, cde/cde, CDe/CdE etc. All genotypes carrying a dominant .D. allele will produce `Rh^(+)` positive phenotype and double recessive genotype .dd. will give rise to Rh negative phenotype.