What is RNA interference ?

Explanation

RNA interference is a biological process in which RNA molecules inhibit gene expression or translation . This is done by neutralising targeted mRNA molecules.
A simplified model for the RNAi pathway is based o two steps, each involving ribonuclease enzyme . In the first step , the trigger RNA (either dsRNA or miRNA primary transcript ) is processed into a short interfering RNA (siRNA) by the RNase II enzymes called Dicer and Drosha . In the second step , siRNAs are loaded into the effectors complex RNA - induced silencing complex (RISC) . The siRNA is unwound during RISC assembly and the single - stranded RNA hybridiezed with mRNA target . This RNAi is seen in plant feeding nematodes.