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State Lyon's hypothesis....

State Lyon's hypothesis.

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Lyon.s hypothesis states that in mammals the necessary dosage compensation is accomplished by the inactivation of one of the X chromosome in females so that both males and females have only one functions X chromosome per cell.
Mary Lyon suggested that Barr bodies represented an inactive chromosome, which in females become tightly coiled into a heterochromatin, a condensed and visible from of chromatin (Lyon.s hypothesis). The number of Barr bodies observed in cell was one less than the number of X-Chromosome. XO females have no Barr body, whereas XXY males have one Barr body.
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What is Lyon's hypothesis?

Based on Lyon's hypothesis, mention the number of Barr bodies in XXY males, XO females.

Knowledge Check

  • Following Lyon's hypothesis identify the number of Barr bodies in OX females .

    A
    Nil
    B
    One
    C
    Two
    D
    Infinity
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