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Discuss any two Allosomal anomalies in...

Discuss any two Allosomal anomalies in human .
Allosomal abnormalities in human beings .

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Mitotic or meiotic non - disjunction of sex chromosomes causes allosomal abnormalities . Several sex chromosomal abnormalities have been detected . E.g Kline felter.s synfrome and Turner.s syndrome .
1. Klinefelter.s Synfrome (XXY Males )
This genetic is due to the presence of an additional copy of the X chromosome resulting in a karyotype of 47,XXY. persons with this syndrome have 47 chromosomes (44AA+XXY) . They are usually sterile males ,tall ,obese , with long limbs , high pitched voice , under developed genetalia and have feeble breast ( gynaecomastia ) development .
2. Turner.s Syndrome (XO Females )
This genetic disorder is due to the loss of a chromosome resulting in a karyotype of 45 ,X . Persons with this syndrome have 45 chromosome (44 autosomes and one X chromosome ) (44 AA + XO) and are sterile females . Low stature , webbed neck , under developed breast , rudimentary gonads lack of menstrual cycle during puberty , are the main symtoms of this syndrome .
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