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Explain the role of microbes in the prod...

Explain the role of microbes in the producation of enzymes & bio active molecules ?

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Microbes used for production of chemicals like organic acids and enzymes . Examples of organic acids producers are Aspergillus niger for citric acid Acetobacter acetic acid, Rhizopus oryzae for fumaric acid , Clostridium butyricum for butyric acid and Lactobacillus for lactic acid . Yeast (Saccharomyces cerevisiae ) and bacteria are used for commercial production of enzymes . Lipases are used in detergent formulations and are used removing oily stains from the laundry Bottled juices are clarified by the use of pectinase , protease and cellulase. Rennet can also be used to bacterium Streptococcus and genetically engineered Streptococci are used as clot buster for removing clots from the blood vessels of patients who have undergone myocardial infarction .
Cyclosporin A , an immunosuppressant used in organ transplantation is produced from the fungus Trichoderma polysporum It is also used for its anti - inflammatory anti fungal and anti parasitic properties Statins produced by the yeast Monascus purpureus have been used to lower blood cholesterol levels . It acts by competitively inhibiting the enzyme responsible for the synthesis of cholesterol Recombinant human insulin has been produced predominantly using E . coli and Saccharomyces cerevisiae for therapeutic use in human .
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