Chromosomes are visible with chromatids at one of the following phases of mitosis :

Options

A. Interphase
B. Prophase
C. Metaphase
D. Anaphase

Answer

To determine in which phase of mitosis chromosomes are visible with chromatids, we can analyze each phase of mitosis step by step.

### Step-by-Step Solution:

1. **Understanding Mitosis Phases**: Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase. Each phase has distinct characteristics regarding chromosome visibility.

2. **Interphase**: The first option is interphase. During interphase, the cell is preparing for division, and chromosomes are not visible as distinct structures. Instead, the DNA is in a relaxed state called chromatin. Therefore, chromosomes are not visible with chromatids in this phase.

3. **Prophase**: The second option is prophase. During prophase, the chromatin condenses into visible chromosomes, and each chromosome consists of two sister chromatids joined at the centromere. This is the phase where chromosomes are clearly visible with their chromatids.

4. **Metaphase**: The third option is metaphase. In this phase, the chromosomes align at the equatorial plate of the cell. While the chromosomes are still visible, they are not in the process of condensing further, and the chromatids are still present but not as distinct as in prophase.

5. **Anaphase**: The fourth option is anaphase. During anaphase, the sister chromatids separate and move towards opposite poles of the cell. Although chromatids are present, they are no longer in the form of visible chromosomes as they are being pulled apart.

6. **Conclusion**: Based on the analysis, the phase of mitosis where chromosomes are visible with chromatids is **prophase**.

### Final Answer:
The correct answer is **Prophase**.

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