In mitosis, the chromosomes can be seen most distinctly during :

Options

A. Interphase
B. Prophase
C. Metaphase
D. Telophase

Answer

**Step-by-Step Solution:**

1. **Understanding Mitosis Phases**: Mitosis consists of several distinct phases: Prophase, Metaphase, Anaphase, and Telophase. Each phase has unique characteristics regarding chromosome visibility.

2. **Analyzing Each Phase**:
- **Interphase**: This is the preparatory phase before mitosis begins. During interphase, chromosomes are not distinctly visible as they are in the form of chromatin, which is less condensed.
- **Prophase**: In this phase, chromosomes begin to condense and become visible. However, they are still not as distinct as they will be later.
- **Metaphase**: During metaphase, chromosomes are fully condensed and align at the equatorial plane of the cell. This is the stage where chromosomes are most distinct and can be easily observed under a microscope.
- **Telophase**: In telophase, chromosomes begin to de-condense back into chromatin, and the nuclear membrane re-forms. Thus, they are not distinctly visible.

3. **Conclusion**: Based on the analysis, the phase in which chromosomes can be seen most distinctly during mitosis is **Metaphase**.

**Final Answer**: The chromosomes can be seen most distinctly during **Metaphase**.

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