Best stage to study the shape of the chromosomes is:

Options

A. `G_(2)`, phase
B. Anaphase
C. Metaphase
D. Prophase

Answer

To determine the best stage to study the shape of chromosomes, we will analyze each phase of the cell cycle provided in the options.

### Step-by-Step Solution:

1. **Understand the Question**: The question asks for the best stage to observe the shape of chromosomes. This implies we need to identify a stage where chromosomes are distinct and well-defined.

2. **Evaluate G2 Phase**:
- The G2 phase is also known as the Gap 2 phase.
- During this phase, the cell is preparing for mitosis, and while it is growing and synthesizing proteins (like tubulin), the chromosomes are not yet condensed.
- **Conclusion**: G2 phase is not suitable for studying the shape of chromosomes.

3. **Evaluate Anaphase**:
- In anaphase, the centromeres split, and the sister chromatids are pulled apart to opposite poles of the cell.
- At this stage, the chromosomes are in the process of separation, which makes them less distinct and not ideal for studying their shape.
- **Conclusion**: Anaphase is also not suitable for studying the shape of chromosomes.

4. **Evaluate Metaphase**:
- During metaphase, chromosomes are aligned at the equatorial plane (metaphase plate).
- This is the stage where chromosomes are most condensed and visible under a microscope, making it the best stage for studying their shape.
- **Conclusion**: Metaphase is the correct answer.

5. **Evaluate Prophase**:
- Prophase is the stage where chromosomes begin to condense and become visible, but they are not yet aligned at the metaphase plate.
- While chromosomes start to take shape, they are not as clearly defined as in metaphase.
- **Conclusion**: Prophase is not the best stage for studying the shape of chromosomes.

### Final Answer:
The best stage to study the shape of the chromosomes is **Metaphase**.

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