Write a short note on Klinefelter's syndrome.

Explanation

### Step-by-Step Text Solution on Klinefelter's Syndrome

1. **Definition**: Klinefelter's syndrome is a chromosomal disorder that occurs in males due to the presence of an extra X chromosome.

2. **Chromosomal Composition**: Normally, human males have a chromosomal composition of 46 chromosomes, which includes 44 autosomes and one X and one Y chromosome (2n = 46). In Klinefelter's syndrome, the karyotype is 47, indicating the presence of an additional X chromosome, resulting in a configuration of 44 autosomes plus 2 X chromosomes and 1 Y chromosome (47, XXY).

3. **Physical Characteristics**: Individuals with Klinefelter's syndrome typically exhibit masculine physical development but may also display some female secondary sexual characteristics. One notable feature is gynecomastia, which is the development of breast tissue in males.

...