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What is Wobble hypothesis?...

What is Wobble hypothesis?

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**Step-by-Step Solution:** 1. **Definition of Wobble Hypothesis**: The Wobble Hypothesis is a theory that explains how tRNA can recognize multiple codons for the same amino acid during protein synthesis. It suggests that the base pairing between the third codon of mRNA and the first anticodon of tRNA is less stringent than the pairing of the first two bases. 2. **Structure of tRNA**: tRNA (transfer RNA) has a cloverleaf structure and is responsible for bringing amino acids to the ribosome during translation. Each tRNA molecule has an anticodon that is complementary to a specific codon on the mRNA. 3. **Base Pairing**: According to the Wobble Hypothesis, the first two bases of the codon and anticodon pair strictly according to the standard base pairing rules (A-U and C-G). However, the third base pairing is more flexible, allowing for non-standard pairings. ...
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