DNA contains nucleobases, sugar and phosphate. Removal of which among these from a DNA sample will not significantly affect the length of DNA?

Options

A. Nucleobases
B. Sugar
C. Phosphate
D. None of these

Answer

To solve the question, we need to analyze the components of DNA and their roles in determining the length of the DNA molecule.

### Step-by-Step Solution:

1. **Identify the Components of DNA**:
DNA is composed of three main components: nucleobases (nitrogenous bases), sugar (deoxyribose), and phosphate groups.

2. **Understand the Structure of DNA**:
DNA has a double-helix structure where the sugar and phosphate groups form the backbone, and the nitrogenous bases project from this backbone. The length of the DNA molecule is primarily determined by the sugar-phosphate backbone.

3. **Consider the Impact of Removing Each Component**:
- **Removing Nucleobases**: If we remove the nitrogenous bases, the sugar-phosphate backbone remains intact. Therefore, the overall length of the DNA molecule will not change significantly because the backbone is still present.
- **Removing Sugar or Phosphate Groups**: If we remove either the sugar or the phosphate groups, we will disrupt the backbone structure of DNA. This would lead to a shortening of the DNA molecule, as the backbone is essential for maintaining the length and integrity of the DNA strand.

4. **Conclusion**:
Based on the analysis, removing the nitrogenous bases will not significantly affect the length of the DNA molecule, while removing sugar or phosphate will.

### Final Answer:
The removal of **nucleobases** (nitrogenous bases) from a DNA sample will not significantly affect the length of DNA.