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Congenital chromosomal and metabolic def...

Congenital chromosomal and metabolic defects in the foetus can be determined by amniocentesis.

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### Step-by-Step Solution: 1. **Understanding Amniocentesis**: - Amniocentesis is a medical procedure used during pregnancy to obtain a sample of amniotic fluid, which contains fetal cells and various substances. - This procedure is typically performed between the 15th and 20th weeks of pregnancy. 2. **Purpose of Amniocentesis**: - The primary purpose of amniocentesis is to diagnose congenital chromosomal abnormalities and metabolic defects in the fetus. - It allows for the analysis of the fetal genetic material and helps in identifying conditions such as Down syndrome, cystic fibrosis, and other genetic disorders. 3. **Procedure**: - A thin needle is inserted through the abdominal wall into the uterus, guided by ultrasound, to collect a small amount of amniotic fluid. - The collected fluid is then sent to a laboratory for analysis. 4. **Analysis of Amniotic Fluid**: - The fetal cells in the amniotic fluid can be cultured and analyzed for chromosomal patterns. - Genetic testing can reveal whether the fetus has any chromosomal abnormalities or metabolic disorders. 5. **Ethical Concerns**: - While amniocentesis is a valuable diagnostic tool, it has been misused in some cases to determine the sex of the fetus. - This misuse can lead to sex-selective abortions, which is illegal and raises ethical concerns regarding gender discrimination and its impact on the male-female ratio in society. 6. **Conclusion**: - The statement that congenital chromosomal and metabolic defects in the fetus can be determined by amniocentesis is correct. - It is important to use this procedure responsibly and ethically to avoid misuse.
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