A : Sickel cell anemia occurs due to the point mutation.
R : mRNA produced from `Hb(s)` gene has GAG instead of GUG.

Sickel cell anemia is the result of ________ mutation in the haemoglobin gene

Assertion (A): Sickle cell anaemia is an example of point mutation. Reason ( R): It is caused by addition or deletion of nitrogenous bases in the DNA or mRNA.

Assertion: Hb^(S) Hb^(S) is homozygous condition of sickle cell anaemia. Reason: It occurs due to substitution of glutamic acid by valine at sixth position in beta -chain of haemoglobin.

Assertion: Hb^(S) Hb^(S) is homozygous condition of sickle cell anaemia. Reason: It occurs due to substitution of glutamic acid by valine at sixth position in beta -chain of haemoglobin.

Given below are assertion and reason. Point out if both are true with reason being correct explanation (A), both are true but reason is not correct explanation (B), assertion is true but reason is wrong ( C) and both are wrong (D). Assertion. Hb^(s)Hb^(s) is homozygous condition of sickle cell anaemia. Reason. It occurs due to substitution of glutamic acid by valine at sixth position in beta -chain of haemoglobin.

Assertion :-Sickle-cell anaemia is caused by the substitution of glutamic acid by valine at the sixth position of the beta globin chain of the hemoglobin moecule. Reason :- It is due to the single base substitution at the sixth codon of the beta globin gene from GUG to GAG.

Assertion :-Sickle-cell anaemia is caused by the substitutin of glutamic acid by valine at the sixth position of the beat globin chain of the hemoglobin moecule. Reason :- It is due to the single base substatution at the sixth codon of the beta lobin gene from GUG to GAG.

Sickle - cell anemia trait is adaptation against malaria. It is due to substitution ( point mutation ) in which

Sickle - cell anemia trait is adaptation against malaria. It is due to substitution ( point mutation ) in which