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What is the significance of juxtaglomeru...

What is the significance of juxtaglomerular apparatus (JGA) in kidney function?

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When glomerular filtration pressure decreases then JGA cells secrete an enzyme Renin which activates angiotensinogen of blood plasma to angiotension-I which changes into angiotensin-II which stimulates adrenal cortex to secrete aldosterone hormone.
Aldosterone causes increased reabsorption of `Na_(+)` and water from the nephric filtrate into interstitial fluid from the distal parts of renal tubule. This increases the blood pressure and GFR. This mechanism is called Renin-Angiotensin mechanism.
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