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Explain the following : (a) Role of Na...

Explain the following :
(a) Role of `Na^(+)` in the gneration of action potential.
(b) Mechanism of generation of light- induced inpulse in the retina .
(c ) Mechanism through which a sound produces a nerve impulse in the inner ear .

Text Solution

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(a) In a stimulated nerve fibre, sodium channels of the neurilemma come in activated state and open. Sodium ions rapidly diffuse from outside to interacellular fluid due to their electrochemical gradient. The potential difference first increases to zero and then rises to `+45 mV` and is called action potential. This causes depolarization of nerve fibre.
(b) When the light rays are foccused on the photoreceptors (rods and cones), then their photopigments are dissociated which activate the transduction protein which activates phosphodiesterase enzyme which changes C - GMP into 5. - GMP. Declined level of C - GMP causes closing of `Na^(+)` channels and hyperpolarisation of photoreceptors and an action potential is generated.
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