Deficiency of iodine leads to a disease called …………… .

Explanation

**Step-by-Step Solution:**

1. **Understanding the Role of Iodine**: Iodine is a crucial element required for the synthesis of thyroid hormones. These hormones are essential for regulating metabolism and overall growth and development in the body.

2. **Identifying the Consequence of Iodine Deficiency**: When there is a deficiency of iodine in the diet, the thyroid gland cannot produce sufficient amounts of thyroid hormones, specifically thyroxine and thyrocalcitonin.

3. **Effects of Low Thyroid Hormone Levels**: The low secretion of thyroid hormones leads to an imbalance in the body's metabolic processes. The thyroid gland attempts to compensate for this deficiency.

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