What causes myxoedema? Write two symptoms of this disease.

Explanation

### Step-by-Step Solution:

1. **Understanding Myxedema**: Myxedema is a condition that arises due to a deficiency of thyroid hormones in the body, particularly in adults. It is often referred to as "girls disease" because it is more commonly observed in females.

2. **Cause of Myxedema**: The primary cause of myxedema is the insufficient secretion of thyroid hormones, specifically thyroxine (T4). When the body does not produce enough of this hormone, it leads to various metabolic issues.

3. **Symptoms of Myxedema**:
- **Low Metabolic Rate**: One of the main symptoms of myxedema is a decreased metabolic rate. Thyroxine plays a crucial role in regulating the basal metabolic rate (BMR), and its deficiency results in a slowdown of metabolic processes in the body.
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