Diabetes insipidus is due to insufficient release of :

Options

A. Insulin
B. Glucagon
C. ADH
D. Thyroxine

Answer

To solve the question regarding diabetes insipidus and its cause, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Diabetes Insipidus**:
- Diabetes insipidus is a condition characterized by excessive thirst and the excretion of large amounts of dilute urine. It is not related to blood sugar levels, which distinguishes it from diabetes mellitus.

2. **Identify the Hormones Involved**:
- The primary hormone involved in regulating water balance in the body is the Antidiuretic Hormone (ADH), also known as vasopressin.

3. **Analyze the Options**:
- **Option 1: Insulin**: This hormone regulates blood glucose levels and is not related to water balance. Therefore, it is not the correct answer.
- **Option 2: Glucagon**: This hormone increases blood glucose levels when they are low and does not play a role in water regulation. Hence, it is also incorrect.
- **Option 3: ADH**: This hormone is crucial for water reabsorption in the kidneys. Insufficient release of ADH leads to diabetes insipidus, making this the correct answer.
- **Option 4: Thyroxine**: This hormone regulates metabolism and is not directly involved in water balance, so it is not the correct answer.

4. **Conclusion**:
- Based on the analysis, the correct answer is **ADH (Antidiuretic Hormone)**, as its insufficient release is responsible for diabetes insipidus.

### Final Answer:
Diabetes insipidus is due to insufficient release of **ADH (Antidiuretic Hormone)**.

---