Protein found in a biological system with a unique three-dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like, change in pH, denaturation of protein takes place. Explain the cause.

Explanation

Due to physical or chemical change, the hydrogen bonds in proteins are disturbed, the protein molecules uncoil from an ordered and specific conformation into a more random conformation. As a result, the protein loses its biological activity. This is called denaturation of proteins.