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The Chargoff's rule says that DNA contai...

The Chargoff's rule says that DNA contains equal amounts of guanine and cytosine and also equimolar amounts of adenine and thymine as :
`G=C and A =T`
(a) Does Chargoff's rule imply that equal amounts of guanine and adenine are present in DNA ?
(b) Does Chargoff's rule imply that the sum of purine residues equals the sum of pyrimidine residues i.e. does `A +G= C+ T`?
(c) Does Chargoff's rule apply only to double stranded DNA or would it apply to each individual strand if the double helical strand were separated into two complementary strands ?

Text Solution

Verified by Experts

(a) No, it does imply that G = A
(b) Yes, it implies `A+G=C+T`
(c ) This rule applies only to double stranded DNA.
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