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Gene therapy aims in correcting diseases...

Gene therapy aims in correcting diseases caused by defective genes. A child is suffering from a disease due to deficiency of ADA enzyme. ADA gene which normally produces the enzyme is missing in the patient. Recommend any two methods to treat the child.

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**Step-by-Step Solution:** 1. **Understanding the Condition**: The child is suffering from a deficiency of the ADA (Adenosine Deaminase) enzyme, which is crucial for the immune system. The absence of this enzyme leads to Severe Combined Immunodeficiency (SCID), making the child vulnerable to infections. 2. **Identifying Treatment Options**: There are two primary methods to treat ADA deficiency: - **Bone Marrow Transplantation**: This method involves transplanting healthy bone marrow from a compatible donor. The new bone marrow can produce the ADA enzyme, thus correcting the deficiency. - **Enzyme Replacement Therapy (ERT)**: In this approach, the missing ADA enzyme is administered to the patient regularly to compensate for the deficiency. This therapy helps manage the symptoms but does not provide a permanent solution. ...
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What are enzyme ? Describe their functions. Name two diseases which are caused due to deficiency of enzymes.

The chemicals used to treat diseases and to reduce the suffering from pain are known as drugs or medicines. The chemicals used in chemotherapy are classified according to their action. For example antipyretics are medicines used to lower the body temperature in high fever. The examples of antipyretics are para ethoxy acetamide and analgin. Analgesics are medicines which relieve pain. They are of two types. (i) Narcotics are medicines which relieve pain by producing sleep and unconsciousness. They are morphine, morphine diacetate (heroin) and codeine. They are habit forming (ii) None narcotic analgesics are not habit forming and do not usually induce sleep. They are aspirin, brufen and butazolidine. Antiseptics are medicines which kill or prevent the growth of micro-organisms. Antiseptics are also used to reduce odours arising out of bacterial decomposition on the surface of the body. They are 2% solution of phenol, dettol (a solution of terpineol and chloro-xylenol) savlon, bithional etc. Tranquillizers are medicine used to relieve mental tension and an anxiety. They act on the nervous system and induce sleep. They may antidepressants (to elevate mood) such as methedrine and vitalin, sedatives (relieve mental agitation and violence) such as diazopam, seconal, luminal and equanil. Antibiotics are medicines produced by micro-organisms such as fungi, bacteria and moulds and are used to kill other microorganisms. They are penicillin (Treat sore throat, bronchitis, pneumonia), streptomycin (active aginst tuberclosis, chloramphenicol treat typhoid, acute fever, urinary infection. Antiseptic action of dettol is due to :

(A) : ADA deficiency is a genetic disease. (R) : It is caused by a mutation of ADA gene.

Read the following five statement (A to E) about gene therapy and select the option with all correct statement: (A) The first clinical gene therapy was given in 1990 to a patient fo emphysema. (B) Gene therapy is a collection of methods that allows correction of a gene defect. (C) Adenosine deaminase (ADA) enzyme is crucial for the immune system to function. (D) Adenosine deaminase (ADA) deficiency is caused due to the duplication of the gene for adenosine deaminase. (E) ADA deficiency can be cured by bone marrow transplantation.

Assertion: Gene therapy is a collection of methods that allows correction of a gene defect diagnosed in a child or embryo Reason :It involves delivery of normal gene into the individual or embryo to take over the function of the non functional gene

Gene therapy is an attempt to correct a genetic defect by providing a normal gene into the individual. By this the normal function can be restored. An alternate method would be to provide the gene product (protein/enzyme) known as replacement thereapy. which would also restore the function.which in your opinion is a better option? Give reason for your answer.

If a pregnant mother is suffering from AIDS, would her child get the disease via genes or placenta.

MODERN PUBLICATION-BIOTECHNOLOGY : PRINCIPLES AND PROCESSES -REVISION EXERCISES (III. SHORT ANSWER TYPE -I QUESTIONS ( A. QUESTION FROM STATE BOARD EXAMINATIONS :))
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  2. Gene therapy aims in correcting diseases caused by defective genes. A ...

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  6. Figure representing the reactions associated with Polymer Chain Reacti...

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  7. BIOTECHNOLOGY & ITS PRINCIPLES

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  8. Write two significance of Bioreactors

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  9. What do you mean by term 'cloning' ?

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  10. How does restriction endonuclease work?

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  11. What are Molecular Scissors? Give one example.

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  12. Write a short note on bioreactor.

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  13. DOWNSTREAM PROCESSING

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  14. What is DNA probe? What are its uses?

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  15. The following photograph shows the result of a technique showing the s...

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  16. Different methods have been suggested to introduce alien DNA into host...

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  17. Write the methods to introduce alien DNA into host cells?

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  18. Draw a neat labelled diagram of plasmid pBR322.

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  19. What is the role of Ori for cloning vector?

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  20. Write the full name of ELISA.

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