Choose the wrong statement:

Options

A. VNTR belong to a class of mini - satellite DNA
B. DNA sequences work on the principle developed by Frederick Sanger
C. HGP was coordinated by US Department of Energy and the National Institute of Health
D. DNA fingerprinting involves identifying similarities in repetitve DNA.

Answer

To solve the question "Choose the wrong statement," we need to evaluate each of the provided statements regarding biotechnology, specifically focusing on VNTR, DNA sequencing, the Human Genome Project, and DNA fingerprinting. Here’s a step-by-step breakdown:

### Step 1: Analyze the first statement
**Statement:** "VNTR belongs to a class of mini-satellite DNA."
- **Explanation:** VNTR (Variable Number Tandem Repeat) is indeed a type of repetitive DNA, and it is classified under mini-satellite DNA. This statement is correct.

### Step 2: Analyze the second statement
**Statement:** "DNA sequence works on the principle developed by Friedrich Sanger."
- **Explanation:** The method of DNA sequencing known as Sanger sequencing was developed by Friedrich Sanger in the 1970s. This statement is also correct.

### Step 3: Analyze the third statement
**Statement:** "Human genome project was coordinated by U.S. Department of Energy and National Institute of Health."
- **Explanation:** The Human Genome Project was indeed coordinated by these two organizations. This statement is correct as well.

### Step 4: Analyze the fourth statement
**Statement:** "DNA fingerprinting involves identifying similarities in a repetitive DNA."
- **Explanation:** DNA fingerprinting actually involves identifying differences in the VNTR regions, which vary from individual to individual. Thus, this statement is incorrect because it states that DNA fingerprinting identifies similarities rather than differences.

### Conclusion
The wrong statement is: **"DNA fingerprinting involves identifying similarities in a repetitive DNA."**

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