What is significance of the Lederberg's experiment?

Explanation

**Step-by-Step Text Solution:**

1. **Introduction to Lederberg's Experiment**: In 1952, Joshua Lederberg conducted a significant experiment known as the Replica Plating Experiment. This experiment aimed to understand the mechanisms of bacterial resistance to antibiotics.

2. **Setup of the Experiment**: Lederberg grew bacterial cells on an agar plate, which is a nutrient-rich medium that supports bacterial growth. After allowing the bacteria to grow, he introduced penicillin, an antibiotic that is effective against many bacteria.

3. **Observation of Results**: Upon the addition of penicillin, most of the bacteria died. However, a few bacteria survived despite the presence of the antibiotic. These surviving bacteria exhibited resistance to penicillin.

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