Which one of the following is not a live vaccine?

Options

A. BCG vaccine
B. Cholera vaccine
C. OPV
D. Measles vaccine

Answer

To determine which of the following vaccines is not a live vaccine, we need to analyze each option provided.

### Step-by-Step Solution:

1. **Understanding Live Vaccines**: Live vaccines contain live, attenuated (weakened) forms of pathogens that can stimulate an immune response without causing the disease. In contrast, non-live vaccines may contain killed pathogens or subunits of the pathogen.

2. **Evaluating the Options**:
- **Option 1: BCG Vaccine**: This vaccine is used for tuberculosis (TB) and contains live, attenuated Mycobacterium bovis. Therefore, this is a live vaccine.

- **Option 2: Cholera Vaccine**: The cholera vaccine contains killed Vibrio cholerae bacteria. Since it uses killed microorganisms, this is not a live vaccine.

- **Option 3: Oral Polio Vaccine (OPV)**: This vaccine contains live, attenuated poliovirus. Thus, this is a live vaccine.

- **Option 4: Measles Vaccine**: The measles vaccine (often part of the MMR vaccine) contains live, attenuated measles virus. Hence, this is also a live vaccine.

3. **Conclusion**: Based on the analysis, the vaccine that is not a live vaccine is the **Cholera Vaccine** (Option 2).

### Final Answer:
The vaccine that is not a live vaccine is the **Cholera Vaccine**.

---