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Adenosine deaminase (ADA) deficiency is ...

Adenosine deaminase (ADA) deficiency is a hereditary disease, where ADA, which is crucial for functioning of immune system is absent. Ex plain how ADA deficiency can be treated.

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ADA deficiency can be treated using bone marrow transplantation or by enzyme therapy. In gene therapy, lymphocytes from the blood of the patient are grown in a 198 culture outside the body. A functional ADA cDNA is then introduced into lymphocytes and returned back to patient.
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Adenosine deaminase deficiency can be permanetly cured by which of the following methods ?

How gene therapy is done to treat ADA deficiency?

Which of the following statements is incorrect about gene therapy in ADA deficiency ?

What is gene therapy ? IIIustrate using the example of adenosine deaminase (ADA) deficiency.

Statement 1: ADA deficiency was the first disease treated by gene therapy. Statement 2: ADA is an autosomal recessive metabolie disorder.

Identify the incorrect statement. (i) The first clinical gene therapy was given by French Anderson. (ii) For a four year old boy with ADA deficiency. (iii) ADA is a autosomal dominant metabolic disorder. (iv) Where patients have non-functioning B - lymphocytes.

Select the suitable answer with respect to gene therapy from the statements given below: Statement A: ADA deficiency or SCID (Severe Combined Immunodeficiency) is an autosomal dominant metabolic disorder. Statement B : It can be cured permanently if ADA gene is introduced into the cells of early embryonic stages.