Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors have over shake flasks?

Explanation

The shake flask method is used for a small-scale production of biotechnological products in a lobaratory. On the other hand, stirred tank bioreactors are used for a large-scale production of biotechnology products.
Stirred tank bioreactors have several advantages over shake flasks. some of them are
- Small volumes of culture can be taken out from the reactor for sampling or testing.
- it has a foam breaker for regulating the foam.
- It has a control system that regulates the temperature and pH.