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Which of the following reactions is appr...

Which of the following reactions is appropriate for converting acetamide to methamine?

A

Carbylamine reaction

B

Hofmann hypobromamide reaction

C

Stephens reaction

D

Gabriels phthalimide synthesis

Text Solution

Verified by Experts

The correct Answer is:
B

The conversion of amide with no substituent on nitrogen to an amine containing one carbon less by the action of alkaline hypobromide or bromine in presence of NaOH. It involves the migration of alkyl or aryl group with its electron pair to electron deficient N from adjacent carbon. The reaction involves the intermediates of isocyanate.
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