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Which of the following has the highest n...

Which of the following has the highest nucleophilicity ?

A

`F^(-)`

B

`OH^(-)`

C

`CH_(3)^(-)`

D

`NH_(2)^(-)`

Text Solution

Verified by Experts

The correct Answer is:
C

Acids form conjugate base after donation of proton. In acids, strong acid forms weak conjugate base while weak acid forms strong conjugate base.
Order of basic strength (nucleophilicity)
`overset(-)(C)H_(3) gt overset(-)(N)H_(2) gt overset(-)(O)H gt overset(-)(F)`
The acidic character of hydrides in period of periodic table increases on moving from left to right side. Hence, their acids have the following order of acidic strength:
`CH_(4) lt NH_(3) lt H_(2)O lt HF`
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Alkyl halides undergo nucleophilic substitution reactions in which halogen atom is replaced by other atom. RX + Nu:^(-) to Nu-R + X^(-) These reactions follow S_(N)1 and S_(N)2 type mechanism, in which S_(N)1 takes place in two steps while S_(N)2 takes place in single step. Due to their tendency to undergo substitution by a large number of nucleophiles, they form a variety of products. Which of the following has highest nucleophilicity?

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