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The disease sickle-cell anaemia is caus...

The disease sickle-cell anaemia is caused by the substitution of `overset("(i)") "____"` by `overset("(ii)") "____"` at the `overset("(iii)") "____"` position of `overset("(iv)") "____"` globin chain of haemoglobin molecule
Which of the following correctly fills the blanks in the above statements ?

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