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When does a cofactor becomes a prostheti...

When does a cofactor becomes a prosthetic group ?

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A cofactor tightly bound to and non-dissociable from the enzyme is called prosthetic group.
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A : Cofactor of an enzyme may be a prosthetic group. R : NAD derived from niacin is a co-enzyme.

Assertion : Coenzymes serve as co-factors in a number of different enzyme catalyzed reactions. Reason : Coenzymes and prosthetic groups are cofactors.