Assertion : Sickle-cell anaemia is an autosome-linked recessive disorder that can be transmitted if both parents are heterozygous for the gene
Reason : In sickle-cell anaemia, haemoglobin molecule undergoes polymerisation under low oxygen tension causing the change in shape in RBC

The mutant haemoglobin moleculae under goes polymerisation under low oxygen tension causing the change in the shape of RBC in case of

Sickle cell anaemia is sec chromosome/autosome linked recessive trait.

Assertion :- In sickle cell anaemia, the shape of RBC becomes elongated sickle like from biconcave disc. Reason :- The mutant haemoglobin molecule undergoes polymerization under low oxygen tension causing the change in shape.

Assertion :- In sickle cell anaemia, the shape of RNC becomes elongated sickle like from biconcave disc. Reason :- The mutant haemoglobin molecule undergoes polymerizatin under low oxygen tension causing the change in shape.

In sickle-cell anaemia , the shape of RBCs under oxygen tension becomes.........

In sickle-cell anaemia , the shape of RBCs under oxygen tension becomes.........

Which of the following is true for sickle cell anaemia regarding the change in shape of RBC?

Which of the following is true for sickle cell anaemia regarding the change in shape of RBC?

Sickle- cell anaemia is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for all the gene (or heterozygous ).The disease is controlled by a single pair of allele, Hb^(A) & Hb^(S) . Out of the three possible genotypes only homozygous individuals for HbS (Hb^(s) Hb^(s)) are lethal. Select the right option in which X,Y and Z are correctly identified