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One of the applications of biotechnology...

One of the applications of biotechnology is to get pest resistant plants. Justify the statement with reference to Bt. cotton.

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Some strains of Bacillus thuringiensis produce protein crystals, (insecticidal protein) that kill insects
Lepidopterans, Coleopterans and Dipterans.Protein crystals are formed during certain phase of their growth.
The "cry "gene, Cry TAC and Cry IIAb from B. thuringiensis coding for the toxins are transferred to cotton plants.
Proteins encoded by these genes control the cotton bollworms.
Bt cotton plants express the Bt toxin gene by producing toxin that provides insect resistance,
Bt toxin protein exists as an inactive prototoxins -insect ingest the inactive toxin, converts to active toxin at alkaline pH of gut of insect which solubilise the crystals.
Toxin binds to surface of midgut epithelial cells create pores that cause cell swelling and lysis and eventually cause death of insect.
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